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The mAbXmise quantification kits are intended to monitor the concentration of therapeutic monoclonal antibodies (mAbs) in samples from patients treated with these mAbs. The kit is a quantitative assay. The test can be performed on plasma (EDTA, heparin or citrate collection tubes) and serum. Assay results are intended to be used by healthcare professionals. Before use, it is important to carefully read the instructions provided with the product.


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mAbXmise monoclonal antibodies quantification kits are In Vitro Diagnostic Medical Devices for laboratory professional use and CE-IVD labeled for Europe by BSI. Assay results are intended to be used by healthcare professionals. The kits are designed to perform absolute quantification by LC-MS (Liquid Chromatography – Mass spectrometry) of specific therapeutic monoclonal antibodies (mAbs) in a patient sample. Assay results are intended to be used by healthcare professionals. Before use, it is important to carefully read the instructions provided with the product. The products are non-refundable. The mAbXmise Kit described has not been cleared by any regulatory entity for diagnostic purposes outside of Europe. Proteomics mAbXmise Kits are not available for sale in all countries.


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Products

Tocilizumab-like - Labelled (Arg,Lys) 13C15N

Application

Quantification of Tocilizumab-like

Specific labelling

Arginine: 13C6,15N4>99%

Lysine: 13C6,15N2, >99%

Description

Labelled Tocilizumab-like is a recombinant, stable isotope labelled monoclonal IgG1-Kappa antibody containing proteotypic peptides derived from Tocilizumab’s originator sequence. Labelled Tocilizumab-like is designed for use as an internal standard for quantitative analysis of Tocilizumab in plasma samples. Tocilizumab targets interleukin 6 (IL-6) receptor.

This product is for research use only and is not intended for diagnostic or therapeutic use.