References

Development of a candidate reference measurement procedure by ID-LC-MS/MS for total tau protein measurement in cerebrospinal fluid (CSF) – Clinical Chemistry and Laboratory Medicine, 61(7), 1235‑1244

IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau – Journal of Proteome Research, 22(4), 1309‑1321

Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype – Analytical Biochemistry, 672, 115156

Absolute quantification of synuclein proteoforms in plasma in patients with Synucleinopathies by LC-MRM mass spectrometry – medRxiv (Cold Spring Harbor Laboratory)

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor – Circulation, 148(2), 144‑158

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives – Pharmaceutics, 15(5), 1477

Development of an ID-LC–MS/MS method using targeted proteomics for quantifying cardiac troponin I in human serum – Clinical Proteomics, 20(1)

Global Discovery and Temporal Changes of Human Albumin Modifications by Pan-Protein Adductomics: Initial Application to Air Pollution Exposure – Journal of the American Society for Mass Spectrometry, 34(4), 595‑607

Quantitation of thrombin-activatable fibrinolysis inhibitor in human plasma by isotope dilution mass spectrometry – Analytical Biochemistry, 2022

Candidate High-Resolution Mass Spectrometry-Based Reference Method for the Quantification of Procalcitonin in Human Serum Using a Characterized Recombinant Protein as a Primary Calibrator – Analytical Chemistry, 94(10), 4146‑4154.. 2022

A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer’s disease – Brain Communications, 4(2). 2022

Accelerating the Validation of Endogenous On-Target Engagement and <em>In-cellulo</em> Kinetic Assessment for Covalent Inhibitors of KRAS G12C in Early Drug Discovery – bioRxiv. 2022

Experimental Medicine Study to Measure Immune Checkpoint Receptors PD‐1 and GITR Turnover Rates In Vivo in Humans – Clinical Pharmacology & ; Therapeutics, 109(6), 1575‑1582. 2021

Development of immunoprecipitation – two-dimensional liquid chromatography – mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients – Journal of Chromatography A, 1651, 462299. 2021

A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM) – Clinical Cancer Research, 27(18), 5028‑5037. 2021

Mass Spectrometry Provides a Highly Sensitive Noninvasive Means of Sequencing and Tracking M-Protein in the Blood of Multiple Myeloma Patients – Journal of Proteome Research, 20(8), 4176‑4185. 2021

A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM) – Clinical Cancer Research, 27(18), 5028‑5037. 2021

Simultaneous Quantification of Adalimumab and Infliximab in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry – Therapeutic Drug Monitoring: April 04, 2019

Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis – Bioanalysis. 2019: Vol 3 No3

Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle – Journal of Translational Autoimmunity. Volume 1, April 2019, 100004

Determination of Cetuximab in Plasma by Liquid Chromatography-High-Resolution Mass Spectrometry Orbitrap With a Stable Labeled 13C,15N-Cetuximab Internal Standard. – Ther Drug Monit. 2019 Aug;41(4):467-475

An Internally Controlled Quantitative Target Occupancy Assay for Covalent Inhibitors – Nature Scientific Reports. 2018 Sep 25;8(1):14312

Simultaneous quantification of adalimumab and infliximab in human plasma by liquid chromatography-tandem mass spectrometry – Therapeutic Drug Monitoring. 2018 Aug;40(4):417-424.

Quantification of cardiac troponin I in human plasma by immunoaffinity enrichment and targeted mass spectrometry – Analytical Bioanalytical Chemistry. 2018 Apr;410(11):2805-2813

Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS – Analytical Chemistry. 2018 Jan 2;90(1):866-871

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor – Cell. 2018 Jan 25;172(3):578-589.e17.

Introducing plasma/serum glycodepletion for the targeted proteomics analysis of cytolysis biomarkers – Talanta. 2017 Aug 1; 170:473-480

Multiplex and accurate quantification of acute kidney injury biomarker candidates in urine using Protein Standard Absolute Quantification (PSAQ) and targeted proteomics – Talanta. March 2017; 164: Pages 77-84

Infliximab quantitation in human plasma by liquid chromatography-tandem mass spectrometry: towards a standardization of the methods? – Analytical Bioanalytical Chemistry. 2017 Feb;409(5):1195-1205

Quantification of active infliximab in human serum with liquid chromatography-tandem mass spectrometry using a tumor necrosis factor alpha -based pre-analytical sample purification and a stable isotopic labeled infliximab bio-similar as internal standard: A target-based, sensitive and cost-effective method – Journal Chromatography A. 2016 Jul 8; 1454:42-8.

Absolute and multiplex quantification of antibodies in serum using PSAQ™ standards and LC-MS – MS. Bioanalysis. 2015;7(10):1237-51

DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments – Journal Proteome Research. 2015 Feb 6;14(2):787-803.

Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry – Clinical Chemistry. 2014 Apr;60(4):683-9

Quantification of human growth hormone in serum with a labeled protein as an internal standard: essential considerations – Analytical Chemistry. 2014 Jul 1;86(13):6525-32.

The Role of Ion Mobility Spectrometry–Mass Spectrometry in the Analysis of Protein Reference Standards – Analytical Chemistry. 2013, 85 (15), pp 7205–7212

PSAQ™ standards for accurate MS-based quantification of proteins: from the concept to biomedical applications – J Mass Spectrometry. 2012 Oct;47(10):1353-63.

Development of a Protein Standard Absolute Quantification (PSAQ™) assay for the quantification of Staphylococcus aureus enterotoxin A in serum – Journal of Proteomics. 2012 Jun 6;75(10):3041-9.

Accurate quantification of cardiovascular biomarkers in serum using Protein Standard Absolute Quantification (PSAQ™) and selected reaction monitoring – Molecular Cellular Proteomics. 2012 Feb;11(2):M111.008235.

Production and use of stable isotope-labeled proteins for absolute quantitative proteomics – Methods Molecular Biology. 2011; 753: 93-115