Therapeutic Drug Monitoring

Breakthrough technology to enhance monoclonal antibody-based treatment

Labelled Trastuzumab 13C15N

Application

Absolute quantification of Herceptin® or its biosimilars

Specific labelling

Arginine: 13C6,15N4, >99%

Lysine: 13C6,15N2, >99%

10 µg     ->    650 €      Quantity  

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Description
Datasheet
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Trastuzumab is a recombinant IgG1 humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. The product contains 10 µg recombinant Trastuzumab isotopically labeled (stable isotopes – non-radioactive) produced in HEK for in vitro research purpose and intended to be used as quantification standard in mass spectrometry analyses.This product is for research use only and is not intended for diagnostic or therapeutic use. PROMISE Advanced Proteomics shall not be held responsible for any damages resulting from the use of this product.